Hidden Licorice Root Benefits: Clinical Studies Reveal Its Power for Hair and Skin
Licorice root benefits date back to pre-ancient Roman times, making it one of the oldest natural ingredients in traditional medicine. Ancient Egyptians valued this powerful botanical for creating smooth, clear complexions. Licorice root contains nearly 300 compounds, with glycyrrhizin as its main active component that provides impressive antioxidant, anti-inflammatory, and antimicrobial properties.
Research shows that licorice root provides remarkable benefits for skin and hair health. The root's extract naturally brightens skin and reduces dark spots through active compounds like glabridin and liquiritin that block the enzyme tyrosinase responsible for melanin production. Clinical studies demonstrate that licorice root's skin benefits match conventional treatments - a cream with licorice root proved as effective as 1% hydrocortisone to treat eczema symptoms. The root's benefits extend to hair care as well, with its natural phytoestrogens that nourish the scalp and strengthen hair follicles while helping to curb dandruff. These clinically-proven benefits are why we've included this powerful ingredient throughout our Max Green Alchemy hair line.
Understanding the Active Compounds in Licorice Root
The amazing healing power of licorice root comes from its rich mix of nearly 300 different compounds with powerful biological effects. These natural ingredients work together to give the skin and hair benefits you'll find in our Max Green Alchemy hair line. Let's take a closer look at the three most important bioactive compounds that make licorice root such a valuable ingredient in natural skincare and haircare.
Glabridin: Tyrosinase Inhibitor for Skin Brightening
Glabridin, the main isoflavone in licorice root, has about 0.08% to 0.35% of the root's dry weight [1]. These small amounts explain why high-quality extracts are so valuable. This compound blocks tyrosinase, the enzyme that makes melanin, at tiny doses of 0.1 to 1.0 µg/ml without affecting DNA synthesis [2]. The blocking effect works best on T1 and T3 tyrosinase isozymes.
Glabridin stands out because it brightens skin in two ways. It stops new melanin from forming by blocking tyrosinase. It also teams up with liquiritin, another licorice compound that helps break down melanin already in your skin [3]. Products with 0.5% glabridin have shown great results in reducing UVB-induced pigmentation and skin redness [2].
The hydroxyl group at glabridin's 4' position gives it the power to block melanin production. This unique structure makes it one of nature's best skin brightening agents that works better than many artificial options.
Glycyrrhizin: Anti-inflammatory and Moisturizing Agent
Glycyrrhizin makes up about 10% of licorice root's dry weight [4]. This active triterpene saponin gives licorice its sweet taste—it's 50 times sweeter than sugar. Beyond sweetness, glycyrrhizin packs some serious anti-inflammatory power through several different ways.
Research shows that glycyrrhizin reduces inflammation by blocking phospholipase A2 and cyclooxygenase activities [4]. It also cuts down on inflammation-causing cytokines like TNF-a, IL-1ß, and IL-6 by suppressing the NF-?B pathway [5]. These properties make it great for soothing irritated scalps—a key benefit in our Max Green Alchemy hair products.
Glycyrrhizin also boosts natural mucus production, which helps keep moisture in both skin and scalp. This keeps everything properly hydrated, creating the perfect environment for healthy hair growth while stopping dryness and flaking.
Licochalcone A: Antioxidant and Oil Regulator
Licochalcone A, a special chalcone found mostly in licorice roots, protects both skin and hair from environmental damage with its powerful antioxidant properties. It fights free radicals and stops superoxide anion production [2], which protects cells from oxidative stress.
Studies show that Licochalcone A helps control oil production by balancing sebum without drying out the skin. This makes it perfect for treating scalp issues like seborrheic dermatitis and dandruff. It also kills harmful microbes that often cause these scalp problems [6].
Licochalcone A's antioxidant strength also stops lipid peroxidation, which protects hair follicles and helps hair grow healthier [4]. That's why we've added licorice root extract to our Max Green Alchemy hair line, tapping into these benefits to help you grow stronger, healthier hair.
Clinical Studies on Licorice Root for Skin Health
Research proves why licorice root remains the life-blood of dermatological care for centuries. Studies confirm what traditional medicine practitioners knew all along - this botanical powerhouse improves skin conditions of all types. These benefits explain why we added it to the Max Green Alchemy hair line.
Reduction in Hyperpigmentation in 4 Weeks
Clinical studies show licorice root works wonders against hyperpigmentation. A double-blind clinical study found that a formula with glabridin (a key licorice compound) reduced ultraviolet-induced hyperpigmentation better than both negative controls and 4% hydroquinone cream, a standard treatment [7]. Lab results show glabridin has up to 16 times the skin lightening effects of hydroquinone [8].
A single-blinded study compared a 7% licorice formulation with 2% hydroquinone to treat melasma. Both groups showed similar depigmentation levels with no statistical difference in results [8]. The results get even better - a split-face study of liquirtin (another active licorice ingredient) showed that both 2% and 4% concentrations worked better than hydroquinone at decreasing pigmentation [8]. These results explain why people increasingly seek licorice root extract benefits as a natural alternative to synthetic lightening agents.
Improved Eczema Symptoms in Topical Trials
Clinical settings have documented licorice root's power against inflammatory skin conditions extensively. A double-blind randomized controlled trial tested different licorice gel concentrations against a base gel for atopic dermatitis treatment. The results were clear - 2% licorice topical gel outperformed the 1% version by reducing erythema, edema, and itching [9].
Medical device creams now use glycyrrhetinic acid (GA), a licorice-derived compound, based on these results. Products have shown clinical results comparable to corticosteroids in easing moderate to severe atopic dermatitis symptoms [10]. Licorice root extract applications improved skin conditions dramatically, matching 1% hydrocortisone's effectiveness without steroid side effects [10]. Dermatologists now recognize these benefits more than ever.
Antioxidant Protection Against UV-Induced Aging
Licorice root offers great photoprotective benefits beyond its anti-inflammatory and brightening properties. Research shows licochalcone A, a major chalcone compound in licorice, blocks solar ultraviolet (sUV)-induced cyclooxygenase-2 (COX-2) expression and prostaglandin E2 (PGE2) generation by inhibiting activator protein 1 (AP-1) transcriptional activity [11]. This process helps prevent UV damage that speeds up aging.
Studies reveal licorice extract blocks sUV-induced phosphorylation of various inflammatory pathways, which reduces oxidative stress damage [11]. Clinical applications show licorice root extract speeds up wound healing, improves remodeling at wound sites, and reduces inflammatory skin condition symptoms effectively [11].
These detailed benefits of licorice root explain its inclusion in our Max Green Alchemy hair line. Our products employ licorice's proven anti-inflammatory, antioxidant, and skin-soothing properties. The result? Not just healthier hair, but a balanced, nourished scalp that forms the foundations for optimal hair growth and vitality.
Clinical Evidence of Licorice Root Benefits for Hair
Scientific research now confirms what traditional medicine practitioners have known for centuries - licorice root's therapeutic effects on hair health extend beyond its skin benefits. Clinical studies continue to provide strong evidence that premium haircare formulations should include this ingredient.
Hair Growth Acceleration in Scalp Application Studies
Licorice extract accelerates hair follicle activity substantially. Hair tonic solutions with 5% and 10% licorice extract matched—and sometimes surpassed—the results of 2% minoxidil, the leading pharmaceutical treatment [12]. Tests on experimental animals showed that 2% hydro-alcoholic licorice extract outperformed minoxidil in hair growth [13].
A newer study published by researchers revealed the mechanism behind these impressive results: 18-ß-glycyrrhetinic acid, a key licorice compound, stimulates dermal papilla cells and outer root sheath cells directly. These cells are crucial for hair growth [14]. This compound also prolongs the anagen (growth) phase by blocking 5a-reductase, an enzyme that converts testosterone to dihydrotestosterone - the hormone responsible for hair loss [14].
Dandruff Reduction via Antimicrobial Properties
The potent antimicrobial and anti-inflammatory properties of licorice root extract provide natural relief from dandruff. Shampoo formulations containing this extract proved highly effective at reducing dandruff and scalp irritation in clinical tests [15]. Regular users reported major improvements in itch, dandruff, and flaking [15].
Researchers found that a 6% glycyrrhetinic acid complex in shampoo changed the scalp microbiome effectively. The formulation reduced Staphylococcus epidermidis (linked to dandruff) while boosting beneficial Cutibacterium acnes [16]. This balanced microbial environment creates ideal conditions for hair growth.
Improved Scalp Hydration and Reduced Itchiness
A tonic with licorice root extract boosted scalp moisture and reduced itching and tautness in a controlled clinical trial [17]. Users noticed their scalp felt more comfortable after just two weeks. Glycyrrhiza inflata root extract, which contains the anti-inflammatory compound licochalcone A, worked exceptionally well at easing symptoms of dry, itchy, and subclinically inflamed scalps [17].
Irritated scalps respond well to licorice root's soothing properties. Clinical settings proved that licorice extract helps relieve redness, itching, and inflammation [18]. These benefits come from licorice's ability to block pro-inflammatory cytokines and minimize histamine-induced reactions [17].
Max Green Alchemy's hair line features licorice root extract as a key ingredient to boost product effectiveness. Learn more about the Scalp Rescue line which uses licorice root in its herbal blend to soothe irritated scalps and create optimal conditions for healthy hair growth.
Application Methods and Product Integration
The best way to add licorice root to your beauty routine starts with picking the right method to get the most out of its healing properties. You can choose from professional products or make your own preparations at home. These options let you tap into licorice root's benefits for your hair and skin health.
Max Green Alchemy Hair Line with Licorice Root
Max Green Alchemy's Scalp Rescue line features licorice root extract as a star ingredient in its special herbal blend. The blend combines licorice root, coltsfoot leaf, yarrow, and other botanicals steeped as a tea infusion. This creates a powerful base for the entire collection [4]. The Scalp Rescue Shampoo mixes this herbal infusion with gentle coconut-based cleansers. It cleans your hair while helping dry, irritated scalps feel better [19]. The Smoothing Balm uses licorice with a plant-based vegan keratin alternative called Vegatin™. This combination repairs hair from within and provides light hold [20].
These products work with natural ingredients instead of harsh chemicals. They help with scalp issues like dryness, itching, and flaking through licorice root's anti-inflammatory properties. The Scalp Rescue line's herbal blend soothes irritated scalps and creates the perfect environment for healthy hair growth.
Topical Serums vs. Infused Oils: What Works Best?
Your specific needs and hair type should guide your choice between different methods. Topical serums pack more licorice extract in a water-based formula that your skin quickly absorbs. Infused oils give you deeper conditioning but might take longer to sink in [3].
Serums with licorice extract work great for hyperpigmentation or melasma. They deliver glabridin—a key skin-brightening compound—right where you need it [3]. Oil-based treatments with licorice root keep your scalp moisturized and protected longer.
Licorice Root Powder in DIY Face Masks
Making your own licorice root treatments saves money while giving you all the benefits. Here's a simple but effective mask recipe:
1 tablespoon licorice root powder
1 tablespoon honey (preferably Manuka)
1 tablespoon plain yogurt
Spread the mixture evenly on your face but stay away from your eyes. Rinse it off with warm water after 15-20 minutes and pat your skin dry. This mask helps hydrate your skin, reduce inflammation, and brighten your complexion. You can also adapt similar DIY recipes to treat scalp problems like dandruff and irritation.
Safety Profile and Contraindications
Licorice root has many healing properties. You need to know about its safety before adding it to your skincare or haircare routine. The right usage helps you get the most benefits with minimal risks.
Topical Use vs. Oral Supplementation Risks
Max Green Alchemy's hair products contain licorice root extract for external use. This is much safer than taking licorice by mouth [2]. The biggest safety concern comes from glycyrrhizin, which can cause problems if you take large amounts orally [1].
Taking glycyrrhizin-containing licorice by mouth can lead to high blood pressure, sodium buildup, and low potassium levels [24]. The World Health Organization and European Scientific Committee on Food say you should not take more than 100 mg of glycyrrhizin daily [25]. The good news is that Max Green Alchemy products are safe because very little absorbs through your skin.
Glycyrrhizin-Free (DGL) Options for Sensitive Users
DGL (deglycyrrhizinated licorice) gives you a safer choice if you have sensitivities. It keeps most healing benefits without glycyrrhizin's risks [26]. Manufacturers remove glycyrrhizin through a special process. This makes DGL safe even if standard licorice extracts cause reactions [27].
DGL works great if you have high blood pressure, low potassium, or take medications that might clash with glycyrrhizin [28]. Research shows you can safely use DGL up to four months without major side effects [1].
Patch Testing and Usage Frequency Guidelines
A patch test is vital before using any licorice root product, especially if you have sensitive skin [2]. Put a tiny amount on your inner forearm. Watch for redness, irritation, or swelling over the next 24-48 hours.
Stay safe with licorice-containing Max Green Alchemy hair products by following these tips:
Start with weekly use and slowly increase as your skin allows
Stop using if irritation shows up
Pregnant women should check with their doctor first [28]
Be careful with medications like corticosteroids, diuretics, and digitalis that interact with licorice [27]
Your body might react differently to licorice root than others. Max Green Alchemy products use balanced amounts of licorice root. This gives you the best results while keeping risks low.
Conclusion
Licorice root has been a wealth of botanical treasure, and with good reason too. The evidence without doubt confirms what traditional healers have known for centuries - this remarkable plant brings extraordinary benefits for both hair and skin health. Scientists have verified these benefits through clinical studies, proving licorice root is more than just traditional wisdom but a scientifically-backed ingredient.
The three key compounds—glabridin, glycyrrhizin, and licochalcone A—create a collaborative effort to deliver powerful therapeutic effects. Glabridin brightens skin by inhibiting melanin production. Glycyrrhizin soothes inflammation and enhances moisture retention. Licochalcone A provides exceptional antioxidant protection and regulates oil production. These compounds are the foundations of a detailed approach to hair and scalp care.
Licorice root's clinically-proven advantages for hair health stand out. Its power to stimulate hair follicle activity is a big deal as it means that it surpasses pharmaceutical treatments in some cases. On top of that, it has natural antimicrobial properties that help curb dandruff while its moisturizing capabilities hydrate dry, irritated scalps.
Max Green Alchemy hair line makes use of these therapeutic properties. Our Scalp Rescue collection has licorice root in a carefully formulated herbal blend. The result? Products that work naturally with your body to promote healthier hair and scalp without harsh chemicals or synthetic ingredients.
Licorice root's power comes with general safety for topical use. All the same, knowing how to use it properly helps maximize benefits while minimizing potential risks. Patch testing before full application will give a perfect match with your unique skin chemistry.
Licorice root stands as nature's answer to common hair and skin concerns. People struggling with scalp irritation, dandruff, or simply seeking healthier hair will find licorice root's clinically-backed benefits are a great way to get more from their hair care routine. We invite you to experience these benefits firsthand through our Max Green Alchemy hair line, where licorice root combines with other therapeutic botanicals to deliver exceptional results.
FAQs
Q1. How does licorice root benefit hair growth? Licorice root extract has been shown to stimulate hair follicles, prolong the growth phase of hair, and improve overall scalp health. It may also inhibit DHT production, a hormone linked to hair loss, and promote cell proliferation crucial for hair follicle development.
Q2. What are the main benefits of licorice root for skin? Licorice root offers multiple skin benefits, including natural skin brightening, reduction of dark spots, anti-inflammatory properties, and moisturizing effects. It also provides antioxidant protection against UV-induced aging and can help soothe various skin conditions.
Q3. Is it safe to apply licorice root to the face daily? Yes, licorice root is generally safe for daily facial application. However, it's always recommended to start with a patch test and gradually increase usage frequency. If you have sensitive skin or any concerns, consult with a dermatologist before daily use.
Q4. How long does it take to see skin lightening effects from licorice root? The time frame for visible skin lightening effects can vary depending on individual factors and the concentration of licorice extract used. Generally, consistent use for at least 4-8 weeks is recommended to see noticeable results in reducing hyperpigmentation and evening out skin tone.
Q5. What makes licorice root effective for treating scalp conditions? Licorice root's effectiveness in treating scalp conditions stems from its potent anti-inflammatory, antimicrobial, and moisturizing properties. It can help reduce dandruff, soothe irritation, balance oil production, and create a healthier scalp environment conducive to optimal hair growth.
References
[1] - https://www.nccih.nih.gov/health/licorice-root
[2] - https://www.smartpractice.com/dermatologyallergy/pdfs/T.R.U.E. TEST Reference Manual.pdf
[3] - https://www.byrdie.com/licorice-extract-for-skin-4777063
[4] - https://www.mdpi.com/2079-9284/9/1/7
[5] - https://pmc.ncbi.nlm.nih.gov/articles/PMC9025446/
[6] - https://pmc.ncbi.nlm.nih.gov/articles/PMC11345200/
[7] - https://pmc.ncbi.nlm.nih.gov/articles/PMC6826613/
[8] - https://jddonline.com/articles/the-use-of-botanical-extracts-in-east-asia-for-treatment-of-hyperpigmentation-an-evidenced-based-rev-S1545961620P0758X/?_page=3
[9] - https://pubmed.ncbi.nlm.nih.gov/14522625/
[10] - https://www.mdpi.com/2079-9284/9/4/75
[11] - https://pmc.ncbi.nlm.nih.gov/articles/PMC4394430/
[12] - https://www.researchgate.net/publication/320802200_Using_hair_growth_activity_physical_stability_and_safety_tests_to_study_hair_tonics_containing_ethanol_extract_of_licorice_Glycyrrhiza_glabra_Linn
[13] - https://www.researchgate.net/publication/260281460_HAIR_GROWTH_STIMULATING_EFFECT_AND_PHYTOCHEMICAL_EVALUATION_OF_HYDRO-ALCOHOLIC_EXTRACT_OF_GLYCYRRHIZA_GLABRA
[14] - https://pubmed.ncbi.nlm.nih.gov/39085137/
[15] - https://pmc.ncbi.nlm.nih.gov/articles/PMC6266641/
[16] - https://onlinelibrary.wiley.com/doi/10.1111/jocd.14623
[17] - https://pubmed.ncbi.nlm.nih.gov/23549137/
[18] - https://www.mdpi.com/2223-7747/13/24/3515
[19] - https://www.maxgreenalchemy.com/Scalp-Rescue-Shampoo_p_10.html
[20] - https://www.maxgreenalchemy.com/Scalp-Rescue-Smoothing-Balm_p_280.html
[24] - https://pmc.ncbi.nlm.nih.gov/articles/PMC3498851/
[25] - https://www.healthline.com/nutrition/licorice-root
[26] - https://dclabs.com/dgl-ex-standardized-de-glycyrrhizinated-licorice-root-extract/
[27] - https://www.webmd.com/vitamins/ai/ingredientmono-881/licorice
[28] - https://www.drugs.com/mtm/licorice.html
Disclaimer: The information in this article is intended for general educational purposes only and is not presented as medical advice or a substitute for professional care. We do not make any medical claims regarding the use of tea tree oil. As with any health-related matter, we recommend consulting your healthcare provider before starting any new skin or hair care regimen, especially if you have underlying conditions or concerns.